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1

Novel Thiazole-Containing Complexing Agents and Luminescence of Their Europum(III) and Terbium(III) Chelates

Veli-Matti Mukkala, Päivi Liitti, Ilkka Hemmilä, Harri Takalo, Cristina Matachescu, Jouko Kankare

Journal:

Helvetica Chimica Acta

Year:

1996

Language:

english

File:

PDF, 744 KB

english, 1996

2

HOMOGENEOUS TIME-RESOLVED IL-2–IL-2Rα ASSAY USING FLUORESCENCE RESONANCE ENERGY TRANSFER

Karolina Stenroos, Pertti Hurskainen, Susann Eriksson, Ilkka Hemmilä, Kaj Blomberg, Christer Lindqvist

Journal:

Year:

1998

Language:

english

File:

PDF, 177 KB

english, 1998

3

Time-resolved fluorescence imaging of europium chelate label in immunohistochemistry and in situ hybridization

Lahja Seveus, Mikko Väisälä, Stina Syrjänen, Minna Sandberg, Ari Kuusisto, Raimo Harju, Juha Salo, Ilkka Hemmilä, Hannu Kojola, Dr. Erkki Soini

Journal:

Cytometry Part A

Year:

1992

Language:

english

File:

PDF, 1.11 MB

english, 1992

4

Fluorescence Quenching-Based Assays for Hydrolyzing Enzymes. Application of Time-Resolved Fluorometry in Assays for Caspase, Helicase, and Phosphatase

Karvinen, Jarkko, Laitala, Ville, Mäkinen, Maija-Liisa, Mulari, Outi, Tamminen, Johanna, Hermonen, Jorma, Hurskainen, Pertti, Hemmilä, Ilkka

Journal:

Analytical Chemistry

Year:

2004

Language:

english

File:

PDF, 183 KB

english, 2004

5

Homogeneous Time-Resolved Fluorescence Quenching Assay (LANCE) for Caspase-3

Karvinen, Jarkko, Hurskainen, Pertti, Gopalakrishnan, Sujatha, Burns, David, Warrior, Usha, Hemmilä, Ilkka

Journal:

Journal of Biomolecular Screening

Year:

2002

File:

PDF, 1.25 MB

2002

6

Caspase multiplexing: simultaneous homogeneous time-resolved quenching assay (TruPoint) for caspases 1, 3, and 6

Jarkko Karvinen, Annika Elomaa, Maija-Liisa Mäkinen, Harri Hakala, Veli-Matti Mukkala, Jari Peuralahti, Pertti Hurskainen, Jari Hovinen, Ilkka Hemmilä

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 282 KB

english, 2004

7

Time-resolved fluorimetry in the study of attachment of staphylococci and streptococci on substrate-bound fibronectin

Pentti Kuusela, Tapio Vartio, Matti Vuento, Erling B. Myhre, Ilkka Hemmilä

Journal:

FEMS Microbiology Letters

Year:

1986

Language:

english

File:

PDF, 389 KB

english, 1986

8

Time-resolved fluorometry: an overview of the labels and core technologies for drug screening applications

Ilkka Hemmilä, Stuart Webb

Journal:

Drug Discovery Today

Year:

1997

Language:

english

File:

PDF, 1.06 MB

english, 1997

9

Syntheses and Properties of Luminescent Lanthanide Chelate Labels and Labeled Haptenic Antigens for Homogeneous Immunoassays

Mikola, Heikki, Takalo, Harri, Hemmila, Ilkka

Journal:

Bioconjugate Chemistry

Year:

1995

Language:

english

File:

PDF, 807 KB

english, 1995

10

Use of fluorescent europium chelates as labels in microscopy allows glutaraldehyde fixation and permanent mounting and leads to reduced autofluorescence and good long-term stability

Lahja Sevéus, Mikko Väisälä, Ilkka Hemmilä, Hannu Kojola, Godfried M. Roomans, Erkki Soini

Journal:

Microscopy Research and Technique

Year:

1994

Language:

english

File:

PDF, 583 KB

english, 1994

11

Determination of hormones by time-resolved fluoroimmunoassay

Timo Lövgren, Ilkka Hemmilä, Kim Pettersson, Jarkko U. Eskola, Eric Bertoft

Journal:

Year:

1984

Language:

english

File:

PDF, 712 KB

english, 1984

12

SPIE Proceedings [SPIE Europto Biomedical Optics '93 - Budapest, Hungary (Sunday 29 August 1993)] Microscopy, Holography, and Interferometry in Biomedicine - Solid surface measurement of room temperature phosphorescence of Pd-coproporphyrin and its application for time-resolved microscopy

Savitsky, Alexander P., Mantrova, Ekaterina Y., Demcheva, Marina V., Ponomarev, Gely V., Hemmila, Ilkka, Soini, Erkki J., Fercher, Adolf F., Lewis, Aaron, Podbielska, Halina, Schneckenburger, Herbert,

Year:

1994

Language:

english

File:

PDF, 382 KB

english, 1994

13

A dissociative fluorescence enhancement technique for one-step time-resolved immunoassays

Kaj R. Blomberg, Veli-Matti Mukkala, Harri H. O. Hakala, Pauliina H. Mäkinen, Mikko U. Suonpää, Ilkka A. Hemmilä

Journal:

Analytical and Bioanalytical Chemistry

Year:

2011

Language:

english

File:

PDF, 178 KB

english, 2011

14

Magnetic Field Dependence of Longitudinal Relaxation Rates of Solutions of Various Protein-Gadolinium3+ Chelate Conjugates

NIEMI, PEKKA, REISTO, TIMO, HEMMILÄ, ILKKA, KORMANO, MARTTI

Journal:

Investigative Radiology

Year:

1991

File:

PDF, 424 KB

1991

15

Europium-labelled target cells in an assay of natural killer cell activity: I. A novel non-radioactive method based on time-resolved fluorescence

Kaj Blomberg, Christer Granberg, Ilkka Hemmilä, Timo Lövgren

Journal:

Journal of Immunological Methods

Year:

1986

Language:

english

File:

PDF, 370 KB

english, 1986

16

Time-resolved fluorometric determination of terbium in aqueous solution

Hemmila, Ilkka.

Journal:

Analytical Chemistry

Year:

1985

Language:

english

File:

PDF, 741 KB

english, 1985

17

Time-resolved detection probe for homogeneous nucleic acid analyses in one-step format

Ville Laitala, Alice Ylikoski, Hanna-Mari Raussi, Pia Ollikka, Ilkka Hemmilä

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 233 KB

english, 2007

18

Simultaneous quantification of two plant viruses by double-label time-resolved immunofluorometric assay

Mart Saarma, Lilian Järvekülg, Ilkka Hemmilä, Harri Siitari, Riivo Sinijärv

Journal:

Journal of Virological Methods

Year:

1989

Language:

english

File:

PDF, 666 KB

english, 1989

19

Time-Resolved FRET -Based Approach for Antibody Detection – A New Serodiagnostic Concept

Saraheimo, Satu, Hepojoki, Jussi, Nurmi, Visa, Lahtinen, Anne, Hemmilä, Ilkka, Vaheri, Antti, Vapalahti, Olli, Hedman, Klaus, Kumar, Nirbhay

Journal:

Year:

2013

Language:

english

File:

PDF, 1.85 MB

english, 2013

20

Proton relaxation enhancement of albumin, immunoglobulin g, and fibrinogen labeled with gd-dtpa

Hannu Paajanen, Timo Reisto, Ilkka Hemmilä, Markku Komu, Pekka Niemi, Martti Kormano

Journal:

Magnetic Resonance in Medicine

Year:

1990

Language:

english

File:

PDF, 351 KB

english, 1990

21

Homogeneous assay based on low quantum yield Sm(III)-donor and anti-Stokes’ shift time-resolved fluorescence resonance energy-transfer measurement

Ville Laitala, Ilkka Hemmilä

Journal:

Analytica Chimica Acta

Year:

2005

Language:

english

File:

PDF, 173 KB

english, 2005

22

A new sensitive assay of human alpha-fetoprotein using time-resolved fluorescence and monoclonal antibodies

Mikko U. Suonpää, Jukka T. Lavi, Ilkka A. Hemmilä, Timo N-E. Lövgren

Journal:

Clinica Chimica Acta

Year:

1985

Language:

english

File:

PDF, 531 KB

english, 1985

23

Europium-labelled target cells in an assay of natural killer cell activity: II. A novel non-radioactive method based on time-resolved fluorescence. Significance and specificity of the method

Kaj Blomberg, Christer Granberg, Ilkka Hemmilä, Timo Lövgren

Journal:

Journal of Immunological Methods

Year:

1986

Language:

english

File:

PDF, 495 KB

english, 1986

24

Genotyping of celiac disease-related-risk haplotypes using a closed-tube polymerase chain reaction analysis of dried blood and saliva disk samples.

Pia Ollikka, Hanna-Mari Raussi, Ville Laitala, Lassi Jaakkola, Jari Hovinen, Ilkka Hemmilä, Alice Ylikoski

Journal:

Analytical Biochemistry

Year:

2009

Language:

english

File:

PDF, 353 KB

english, 2009

25

Determination of cytotoxic T lymphocyte activity by time-resolved fluorometry using europium-labelled concanavalin A-stimulated cells as targets

Christer Granberg, Kaj Blomberg, Ilkka Hemmilä, Timo Lövgren

Journal:

Journal of Immunological Methods

Year:

1988

Language:

english

File:

PDF, 381 KB

english, 1988

26

Comparison of Homogeneous Single-Label Fluorometric Binding Assays: Fluorescence Polarization and Dual-Parametric Quenching Resonance Energy Transfer Technique

Härmä, Harri, Sarrail, Gregoire, Kirjavainen, Jonna, Martikkala, Eija, Hemmilä, Ilkka, Hänninen, Pekka

Journal:

Analytical Chemistry

Year:

2010

Language:

english

File:

PDF, 484 KB

english, 2010

27

Co-fluorescence enhancement system based on pivaloyltrifluoroacetone and yttrium for the simultaneous detection of europium, terbium, samarium and dysprosium

Yong-Yuan Xu, Ilkka A. Hemmilä

Journal:

Analytica Chimica Acta

Year:

1992

Language:

english

File:

PDF, 655 KB

english, 1992

28

Development of luminescent lanthanide chelate labels for diagnostic assays

Ilkka Hemmilä, Veli-Matti Mukkala, Harri Takalo

Journal:

Journal of Alloys and Compounds

Year:

1997

Language:

english

File:

PDF, 580 KB

english, 1997

29

Profiling the hydA gene and hydA gene transcript levels of Clostridium butyricum during continuous, mixed-culture hydrogen fermentation

Katariina E.S. Tolvanen, Perttu E.P. Koskinen, Hanna-Mari Raussi, Alice I. Ylikoski, Ilkka A. Hemmilä, Ville P. Santala, Matti T. Karp

Journal:

International Journal of Hydrogen Energy

Year:

2008

Language:

english

File:

PDF, 363 KB

english, 2008

30

Lanthanide chelates as labels in in situ hybridization and immunohistochemistry

Lahja Sevéus, Ari Kuusisto, Mikko Väisälä, Ilkka Hemmilä, Erkki Soini

Journal:

Micron and Microscopica Acta

Year:

1990

Language:

english

File:

PDF, 106 KB

english, 1990

31

Synthesis of Europium(III) Chelates Suitable for Labeling of Bioactive Molecules

Takalo, Harri, Mukkala, Veli-Matti, Mikola, Heikki, Liitti, Paivi, Hemmila, Ilkka

Journal:

Bioconjugate Chemistry

Year:

1994

Language:

english

File:

PDF, 499 KB

english, 1994

32

Homogeneous Assay Based on Anti-Stokes' Shift Time-Resolved Fluorescence Resonance Energy-Transfer Measurement

Laitala, Ville, Hemmilä, Ilkka

Journal:

Analytical Chemistry

Year:

2005

Language:

english

File:

PDF, 108 KB

english, 2005

33

A versatile method for quantification of DNA and PCR products based on time-resolved Euiii luminescence

Song, Bo, Vandevyver, Caroline D. B., Deiters, Emmanuel, Chauvin, Anne-Sophie, Hemmilä, Ilkka, Bünzli, Jean-Claude G.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2008

Language:

english

File:

PDF, 653 KB

english, 2008

34

Europium as a label in time-resolved immunofluorometric assays

Ilkka Hemmilä, Salifu Dakubu, Veli-Matti Mukkala, Harri Siitari, Timo Lövgren

Journal:

Analytical Biochemistry

Year:

1984

Language:

english

File:

PDF, 690 KB

english, 1984

35

Quantitative monitoring of a hydrogen-producing Clostridium butyricum strain from a continuous-flow, mixed culture bioreactor employing real-time PCR

Katariina E.S. Tolvanen, Perttu E.P. Koskinen, Alice I. Ylikoski, Pia K. Ollikka, Ilkka A. Hemmilä, Jaakko A. Puhakka, Matti T. Karp

Journal:

International Journal of Hydrogen Energy

Year:

2008

Language:

english

File:

PDF, 349 KB

english, 2008

36

Novel detection strategies for drug discovery

Ilkka A. Hemmilä, Pertti Hurskainen

Journal:

Drug Discovery Today

Year:

2002

Language:

english

File:

PDF, 3.40 MB

english, 2002

37

Analytical application of the co-fluorescence effect in detection of europium, terbium, samarium and dysprosium with time-resolved fluorimetry

Yong-Yuan Xu, Ilkka A. Hemmilä

Journal:

Year:

1992

Language:

english

File:

PDF, 472 KB

english, 1992

38

Influence of Coupling Method on the Luminescence Properties, Coupling Efficiency, and Binding Affinity of Antibodies Labeled with Europium(III) Chelates

Karşılayan, Huriye, Hemmilä, Ilkka, Takalo, Harri, Toivonen, Airi, Pettersson, Kim, Lövgren, Timo, Mukkala, Veli-Matti

Journal:

Bioconjugate Chemistry

Year:

1997

Language:

english

File:

PDF, 203 KB

english, 1997

39

Time-resolved lanthanide luminescence for lab-on-a-chip detection of biomarkers on cancerous tissues

Song, Bo, Sivagnanam, Venkataragavalu, Vandevyver, Caroline D. B., Hemmilä, Ilkka, Lehr, Hans-Anton, Gijs, Martin A. M., Bünzli, Jean-Claude G.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2009

Language:

english

File:

PDF, 719 KB

english, 2009

40

Nonradioactive GTP Binding Assay to Monitor Activation of G Protein-Coupled Receptors

Frang, Heini, Mukkala, Veli-Matti, Syystö, Rita, Ollikka, Pia, Hurskainen, Pertti, Scheinin, Mika, Hemmilä, Ilkka

Journal:

Assay and Drug Development Technologies

Year:

2003

Language:

english

File:

PDF, 202 KB

english, 2003

41

Synthesis and Luminescence of Novel EuIII Complexing Agents and Labels with 4-(Phenylethynyl)pyridine Subunits

Harri Takalo, Ilkka Hemmilä, Timo Sutela, Martti Latva

Journal:

Helvetica Chimica Acta

Year:

1996

Language:

english

File:

PDF, 844 KB

english, 1996

42

Time-Resolution in Fluorometry Technologies, Labels, and Applications in Bioanalytical Assays

Hemmilá, Ilkka, Mukkala, Veli-Matti

Journal:

Critical Reviews in Clinical Laboratory Sciences

Year:

2001

Language:

english

File:

PDF, 764 KB

english, 2001

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